Single-Use Mixing

Singota’s single‑use mixing technology simplifies formulation support with a flexible, low‑shear, purpose‑built solution. Designed for fast, out‑of‑the‑box operation, it safeguards sensitive proteins, reduces setup time, and streamlines formulation development while protecting product quality.

Mixing, Made Smarter

Our singleuse mixing technology provides a purposebuilt approach for producing homogenized mixtures during formulation. Each vessel incorporates lowshear mixing within a fully closed, aseptic design to support process consistency and product quality. Supported by Singota’s experience across applications, these singleuse mixing vessels are designed to facilitate setup and operation throughout the formulation process.

Supported Mixing Applications

  • Formulation
  • Buffer & Media Preparation
  • Ultrafiltration/Diafiltration
  • Compounding
Three large glass bottles with tubing and sterile connectors in a laboratory cabinet or hood area with perforated metal back panel junupdated   low shear junupdated   low shear

Low-Shear Performance, Proven in Practice

The advanced single‑use mixing technology used by Singota redefines small‑volume biopharmaceutical mixing. Its low‑shear impeller delivers 2× lower shear forces than comparable systems, helping protect sensitive molecules while enabling consistent mixing from 50 mL to 20 L. As the first bottle‑based mixing system for commercial biomanufacturing, this technology offers true out‑of‑the‑box setup in under two minutes and reduced capital investment through integration with standard mixing plates—supporting Singota’s focus on faster, flexible, efficient solutions.

Key Features of the Technology

  • Bottom‑Mounted Low‑Shear Impeller: 4‑blade
    design delivers powerful mixing while minimizing
    protein degradation
  • Viscous & Powder Mixing: Efficient performance
    with viscous solutions (≤500 cP) and rapid
    powder dissolution

  • Aseptic Cap: One‑piece molded cap with
    continuous flow path and >99.9% product
    recovery

Lower Shear Forces
Product Protection During Formulation
Cost Savings
Up to 10× Cost Savings
Ready: STAT
Start Formulation in Less Than 2 Minutes

Learn More About Cutting-Edge Technology

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    Single Use Mixing